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Moreover, P2Y12 receptor antagonist cangrelor, combined with metabolism inhibitors, reduced mitochondrial respiratory rate and showed enhanced antiplatelet aggregatory activity ( 4.2.2 Antioxidants Oxidative stress can induce mitochondrial damage and is a key contributor to thrombotic events in diabetes ( 1 (CoQ1) reduced the mtROS and improved the ΔΨM in platelet mitochondria (Sacks et al., 2021)

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Research has shown that B12 deficiency can contribute to feelings of depression and anxiety